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Efna1 Antibody

Rare Species
  • 中文名稱：
    Efna1兔多克隆抗體
  • 貨號：
    CSB-PA007460LA01RA
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Rattus norvegicus (Rat) Efna1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Efna1 antibody; Epgl1 antibody; Lerk1 antibody; Ephrin-A1 antibody; EPH-related receptor tyrosine kinase ligand 1 antibody; LERK-1 antibody; Immediate early response protein B61) [Cleaved into: Ephrin-A1 antibody; secreted form] antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Rat
  • 免疫原：
    Recombinant Rat Ephrin-A1 protein (18-182AA)
  • 免疫原種屬：
    Rattus norvegicus (Rat)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，Efna1 Antibody (CSB-PA007460LA01RA)，的標(biāo)記方式是Non-conjugated。對于Efna1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA007460LB01RA Efna1 Antibody, HRP conjugated ELISA
    FITC CSB-PA007460LC01RA Efna1 Antibody, FITC conjugated
    Biotin CSB-PA007460LD01RA Efna1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.
  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.; [Ephrin-A1, secreted form]: Secreted.
  • 蛋白家族：
    Ephrin family
  • 數(shù)據(jù)庫鏈接：