FAM129B (Ab-712) Antibody

說明書

中文名稱：

FAM129B (Ab-712)兔多克隆抗體
貨號：

CSB-PA998601
規(guī)格：

￥2024
圖片：
Western blot analysis of extracts from 3T3 and DU145 cells using Niban-like protein(Ab-712) antibody.

Immunofluorescence staining of methanol-fixed Hela cells using Niban-like protein(Ab-712) antibody.
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) FAM129B Polyclonal antibody
Uniprot No.：

Q96TA1
基因名：

FAM129B
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Peptide sequence around aa.710~714 (Q-V-S-S-P) derived from Human Niban-like protein.
免疫原種屬：

Homo sapiens (Human)
克隆類型：

Polyclonal
純化方式：

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
濃度：

It differs from different batches. Please contact us to confirm it.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:1000
IF	1:100-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro.
基因功能參考文獻：
1. activated EGFR phosphorylates the Y593 residue of the protein known as family with sequence similarity 129, member B (FAM129B), which is overexpressed in many types of human cancer. PMID: 26721396
2. The rapid induction of apoptosis in FAM129B knockdown cells was reversed by co-transfection with recombinant FAM129B, indicating that its effect on apoptosis was specific. PMID: 21148485
3. Phosphorylation of FAM129B has a role in controlling melanoma cell invasion. PMID: 19362540
亞細胞定位：

Cytoplasm, cytosol. Cell junction, adherens junction. Membrane; Lipid-anchor. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation.
蛋白家族：

Niban family
數(shù)據(jù)庫鏈接：

HGNC: 25282

OMIM: 614045

KEGG: hsa:64855

STRING: 9606.ENSP00000362409

UniGene: Hs.522401