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  4. FBXO9 Antibody

FBXO9 Antibody

  • 中文名稱：
    FBXO9兔多克隆抗體
  • 貨號：
    CSB-PA891719LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA891719LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA891719LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) FBXO9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FBXO9
  • 別名：
    Cross-immune reaction antigen 1 antibody; dJ341E18.2 antibody; DKFZp434C0118 antibody; F-box only protein 9 antibody; Fbp24 antibody; FBX09 antibody; FBX9 antibody; FBX9_HUMAN antibody; Fbxo9 antibody; KIAA0936 antibody; NY REN 57 antibody; OTTHUMP00000016628 antibody; OTTHUMP00000016629 antibody; OTTHUMP00000214588 antibody; Renal carcinoma antigen NY-REN-57 antibody; VCIA1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human F-box only protein 9 protein (13-111AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，F(xiàn)BXO9 Antibody (CSB-PA891719LA01HU)，的標(biāo)記方式是Non-conjugated。對于FBXO9 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA891719LB01HU FBXO9 Antibody, HRP conjugated ELISA
    FITC CSB-PA891719LC01HU FBXO9 Antibody, FITC conjugated
    Biotin CSB-PA891719LD01HU FBXO9 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13588

    OMIM: 609091

    KEGG: hsa:26268

    STRING: 9606.ENSP00000244426

    UniGene: Hs.216653