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FBXW12 Antibody, HRP conjugated

  • 中文名稱(chēng)：
    FBXW12兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA751062LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) FBXW12 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FBXW12
  • 別名：
    FBXW12 antibody; FBW12 antibody; FBXO12 antibody; FBXO35F-box/WD repeat-containing protein 12 antibody; F-box and WD-40 domain-containing protein 12 antibody; F-box only protein 35 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human F-box/WD repeat-containing protein 12 protein (1-250AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
  • 基因功能參考文獻(xiàn)：
    1. FBXW12 gene is deleted in approximately ten percent of the epithelial ovarian cancer cases studied; such deletions comprised either the FBXW12 promoter or the mRNA-encoding region. PMID: 26617728
    2. FBXW12 functions as an E3 ligase constituent to ubiquitinate and degrade IL-22R and that therapeutic FBXW12 inhibition may enhance IL-22 signaling and bolster mucosal host defense and infection containment. PMID: 26171402
    3. FBXO35 gene had a ubiquitously low expression pattern in most human adult tissues. FBXO35 gene was found located in chromosome 3p21. PMID: 15040455
  • 組織特異性：
    Ubiquitously expressed.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 20729

    OMIM: 609075

    KEGG: hsa:285231

    STRING: 9606.ENSP00000296438

    UniGene: Hs.288793