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FGFR1OP2 Antibody

  • 中文名稱：
    FGFR1OP2兔多克隆抗體
  • 貨號：
    CSB-PA008644LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: FGFR1OP2 antibody at 6µg/ml
      Lane 1: Mouse gonadal tissue
      Lane 2: Human placenta tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 30, 25, 21 kDa
      Observed band size: 30 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) FGFR1OP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FGFR1OP2
  • 別名：
    DKFZp564O1863 antibody; FGFR1 oncogene partner 2 antibody; FGFR1OP2 antibody; FGOP2_HUMAN antibody; Fibroblast growth factor receptor 1 oncogene partner 2 antibody; HSPC123 antibody; HSPC123 like antibody; WIT3.0 antibody; Wound inducible transcript 3.0 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human FGFR1 oncogene partner 2 protein (1-172AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，F(xiàn)GFR1OP2 Antibody (CSB-PA008644LA01HU)，的標(biāo)記方式是Non-conjugated。對于FGFR1OP2 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA008644LB01HU FGFR1OP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA008644LC01HU FGFR1OP2 Antibody, FITC conjugated
    Biotin CSB-PA008644LD01HU FGFR1OP2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May be involved in wound healing pathway.
  • 基因功能參考文獻(xiàn)：
    1. The patient with minor allele of ss518063493 may be associated with excessive atrophy of edentulous mandible whereas the patients with that of rs840869 are not associated in Korean population. PMID: 22880093
    2. patients with the minor allele of rs840869 or rs859024 of FGFR1OP2 were associated with excessive atrophy of edentulous mandible PMID: 21283824
    3. FGFR1OP2/wit3.0 may regulate cell motility and stimulate wound closure. PMID: 19959814
    4. FGFR1OP2 is a new FGFR1 fusion gene involving a chromosomes 12X8 translocation in a 8p11 myeloproliferative syndrome patient. PMID: 15034873
  • 相關(guān)疾?。?/div>
    A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    SIKE family
  • 組織特異性：
    Expressed in bone marrow, spleen and thymus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 23098

    OMIM: 608858

    KEGG: hsa:26127

    STRING: 9606.ENSP00000229395

    UniGene: Hs.591162