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  4. FOXI1 Antibody, FITC conjugated

FOXI1 Antibody, FITC conjugated

  • 中文名稱：
    FOXI1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA622520LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) FOXI1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FOXI1
  • 別名：
    FKH10 antibody; FKHL10 antibody; Forkhead (Drosophila) like 10 antibody; Forkhead box I1 antibody; Forkhead box protein I1 antibody; Forkhead like 10 antibody; Forkhead related activator 6 antibody; Forkhead related transcription factor 6 antibody; Forkhead-related protein FKHL10 antibody; Forkhead-related transcription factor 6 antibody; FOXI1 antibody; FOXI1_HUMAN antibody; FREAC 6 antibody; FREAC-6 antibody; FREAC6 antibody; Hepatocyte nuclear factor 3 forkhead homolog 3 antibody; HFH 3 antibody; HFH-3 antibody; HFH3 antibody; HNF 3/fork head homolog 3 antibody; HNF-3 fork-head homolog 3 antibody; HNF-3/fork-head homolog 3 antibody; Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds antibody; MGC34197 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Forkhead box protein I1 protein (183-343AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules.
  • 基因功能參考文獻：
    1. study reveals that Foxi1/miR-491-5p/Wnt3a/beta-catenin signaling is critical in the progression of GC. Targeting the pathway described in this study may open up new prospects to restrict the progression of gastric cancer PMID: 28358374
    2. We found no evidence for a significant association between mutations of KCNJ10 and FOXI1 with SLC26A4 in Pendred syndrome/enlarged vestibular aqueducts. PMID: 23965030
    3. No FOXI1 mutations were present in bilateral deafness patients with inner ear malformation. PMID: 22412181
    4. SLC26A4, FOXI1 and KCNJ10 are not major determinants in unilateral deafness and enlarged vestibular aqueduct PMID: 20621367
    5. C/EBP alpha and HNF-3 gamma cooperatively regulate CYP3A4 expression in hepatic cells by a mechanism that probably involves chromatin remodeling. PMID: 12695546
    6. Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase complex at these locations. PMID: 19214237

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  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3815

    OMIM: 601093

    KEGG: hsa:2299

    STRING: 9606.ENSP00000304286

    UniGene: Hs.87236