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FUK Antibody

  • 中文名稱：
    FUK兔多克隆抗體
  • 貨號(hào)：
    CSB-PA847604LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA847604LA01HU diluted at 1:300 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA847604LA01HU diluted at 1:300 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of MCF-7 cells with CSB-PA847604LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) FUK Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FUK
  • 別名：
    1110046B12Rik antibody; FLJ39408 antibody; Fucokinase antibody; FUK antibody; FUK_HUMAN antibody; L-fucose kinase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human L-fucose kinase protein (579-758AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，F(xiàn)UK Antibody (CSB-PA847604LA01HU)，的標(biāo)記方式是Non-conjugated。對于FUK Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA847604LB01HU FUK Antibody, HRP conjugated ELISA
    FITC CSB-PA847604LC01HU FUK Antibody, FITC conjugated
    Biotin CSB-PA847604LD01HU FUK Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.
  • 基因功能參考文獻(xiàn)：
    1. Ectopic expression of FUK inhibits the formation and the proteolytic activities of invadopodia, suggesting that the fucose salvage pathway might control melanoma invasion through invadopodium-mediated ECM remodeling. FUK depletion in WM793 melanoma cells at least partially abrogated the L-fucose-mediated inhibition of invadopodium formation. PMID: 29924834
  • 蛋白家族：
    GHMP kinase family
  • 組織特異性：
    Expressed in fibroblasts.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29500

    OMIM: 608675

    KEGG: hsa:197258

    STRING: 9606.ENSP00000288078

    UniGene: Hs.7907