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GALM Antibody

  • 中文名稱：
    GALM兔多克隆抗體
  • 貨號：
    CSB-PA850268HA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: GALM antibody at 2µg/ml
      Lane 1: Mouse kidney tissue
      Lane 2: Rat adrenal gland tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 38 kDa
      Observed band size: 38 kDa
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA850268HA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA850268HA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GALM Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GALM
  • 別名：
    Aldose 1 epimerase antibody; Aldose 1-epimerase antibody; BLOCK25 antibody; Galactomutarotase antibody; Galactose mutarotase antibody; Galm antibody; GALM_HUMAN antibody; IBD1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Aldose 1-epimerase protein (2-342AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，GALM Antibody (CSB-PA850268HA01HU)，的標(biāo)記方式是Non-conjugated。對于GALM Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA850268HB01HU GALM Antibody, HRP conjugated ELISA
    FITC CSB-PA850268HC01HU GALM Antibody, FITC conjugated
    Biotin CSB-PA850268HD01HU GALM Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose.
  • 基因功能參考文獻(xiàn)：
    1. This study demonistrated that polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus. PMID: 21339755
    2. Identification and characterisation of human aldose 1-epimerase. PMID: 12753898
    3. The enzyme is a monomer and has a similar structure to the Lactococcus lactis mutarotase. PMID: 15026423
    4. Gene encodes a functional aldose 1-epimerase (mutarotase). The enzyme exhibits (approx. four-fold) preference for galactose over glucose. Mutation E307A results in no detactable activity. PMID: 12753898
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Aldose epimerase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24063

    OMIM: 137030

    KEGG: hsa:130589

    STRING: 9606.ENSP00000272252

    UniGene: Hs.435012