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GALNT7 Antibody

  • 中文名稱：
    GALNT7兔多克隆抗體
  • 貨號：
    CSB-PA773016LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: GALNT7 antibody at 0.1µg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 76 kDa
      Observed band size: 76 kDa
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA773016LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GALNT7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GALNT7
  • 別名：
    GalNAc T7 antibody; GalNAc-T7 antibody; GalNAcT7 antibody; GALNT 7 antibody; Galnt7 antibody; GALT7_HUMAN antibody; N acetylgalactosaminyltransferase 7 antibody; N-acetylgalactosaminyltransferase 7 antibody; Polypeptide GalNAc transferase 7 antibody; Polypeptide N acetylgalactosaminyltransferase 7 antibody; pp GaNTase 7 antibody; pp-GaNTase 7 antibody; Protein UDP acetylgalactosaminyltransferase 7 antibody; Protein-UDP acetylgalactosaminyltransferase 7 antibody; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 7 antibody; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 7 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human N-acetylgalactosaminyltransferase 7 protein (201-500AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，GALNT7 Antibody (CSB-PA773016LA01HU)，的標(biāo)記方式是Non-conjugated。對于GALNT7 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA773016LB01HU GALNT7 Antibody, HRP conjugated ELISA
    FITC CSB-PA773016LC01HU GALNT7 Antibody, FITC conjugated
    Biotin CSB-PA773016LD01HU GALNT7 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
  • 基因功能參考文獻(xiàn)：
    1. miR-494 and GALNT7 play oncogenic roles in nasopharyngeal carcinoma. PMID: 26503214
    2. High expression of GALNT7 promotes migration and invasion and lymph node metastasis in esophageal squamous cell carcinoma. PMID: 27619677
    3. GALNT7 and CDK16 were confirmed to be the direct targets of miR-494. These results suggested that miR-494 play an inhibitory role in the tumorigenesis of NPC PMID: 25809707
    4. The study of miR-34a, miR-34c and its novel target, GALNT7, may serve as novel potential makers for laryngeal squamous cell carcinoma therapy. PMID: 24482044
    5. miR-214 is a new regulator of GALNT7, and both miR-214 and GALNT7 play important roles in the pathogenesis of cervical cancer PMID: 22399294
    6. Ectopic expression of miR-30b/30d promoted the metastatic behavior of melanoma cells by directly targeting the GalNAc transferase GALNT7. PMID: 21741600
    7. MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7 PMID: 19844573

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  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性：
    Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4129

    OMIM: 605005

    KEGG: hsa:51809

    STRING: 9606.ENSP00000265000

    UniGene: Hs.548088