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  4. GMIP Antibody, Biotin conjugated

GMIP Antibody, Biotin conjugated

  • 中文名稱：
    GMIP兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA878952LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GMIP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GMIP
  • 別名：
    ARHGAP46 antibody; GEM interacting protein antibody; GEM-interacting protein antibody; GMIP antibody; GMIP_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human GEM-interacting protein (719-858AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Stimulates, in vitro and in vivo, the GTPase activity of RhoA.
  • 基因功能參考文獻(xiàn)：
    1. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages PMID: 25173885
    2. during exocytosis, actin depolymerization commences near the secretory organelle, not the plasma membrane, and secretory granules use a JFC1- and GMIP-dependent molecular mechanism to traverse cortical actin. PMID: 22438581
    3. signalling pathways controlled by two proteins of the Ras superfamily, RhoA and Gem, are linked via the action of the RhoGAP protein Gmip PMID: 12093360
    4. Variations in the GMIP gene can confer susceptibility to major depressive disorder. PMID: 16086184
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24852

    OMIM: 609694

    KEGG: hsa:51291

    STRING: 9606.ENSP00000203556

    UniGene: Hs.49427