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GMPS Antibody

  • 中文名稱：
    GMPS兔多克隆抗體
  • 貨號：
    CSB-PA009582ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: GMPS antibody at 2.69µg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: HL60 whole cell lysate
      Lane 3: MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to Rabbit IgG at 1/10000 dilution
      Predicted band size: 77, 66 kDa
      Observed band size: 77 kDa
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA009582ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GMPS Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GMPS
  • 別名：
    GATD7 antibody; Glutamine amidotransferase antibody; GMP synthase [glutamine hydrolyzing] antibody; GMP synthase [glutamine-hydrolyzing] antibody; GMP synthetase antibody; Gmps antibody; GUAA_HUMAN antibody; Guanine monophosphate synthase antibody; Guanine monphosphate synthetase antibody; Guanosine 5' monophosphate synthase antibody; MLL/GMPS fusion protein antibody; Testicular tissue protein Li 82 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human GMP synthase [glutamine-hydrolyzing] protein (394-693AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
  • 基因功能參考文獻(xiàn)：
    1. Three genes-ATP6V1G1 in 9q32, GMPS in 3q25.31, and TBX5 in 12q24.21-exhibited concomitant hypermethylation and decreased expression. The i(12p)-positive cells displayed global hypomethylation of gene-poor regions on 12p, a footprint previously associated with constitutional and acquired gains of whole chromosomes as well as with X-chromosome inactivation in females PMID: 26890086
    2. Cytoplasmic sequestration of GMPS requires ubiquitylation by TRIM21. PMID: 24462112
  • 相關(guān)疾病：
    A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocation t(3,11)(q25,q23) with KMT2A/MLL1.
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4378

    OMIM: 600358

    KEGG: hsa:8833

    STRING: 9606.ENSP00000419851

    UniGene: Hs.591314