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GPR110 Antibody

  • 中文名稱：
    GPR110兔多克隆抗體
  • 貨號(hào)：
    CSB-PA002753
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 3T3 cells using GPR110 Polyclonal Antibody
    • Western Blot analysis of NIH-3T3 K562 cells using GPR110 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    G protein coupled receptor 110 antibody; G protein coupled receptor KPG_012 antibody; G protein coupled receptor PGR19 antibody; G-protein coupled receptor KPG_012 antibody; G-protein coupled receptor PGR19 antibody; GP110_HUMAN antibody; GPR110 antibody; HGPCR36 antibody; KPG_012 antibody; PGR19 antibody; Probable G protein coupled receptor 110 antibody; Probable G-protein coupled receptor 110 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human GPR110.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Orphan receptor.
  • 基因功能參考文獻(xiàn)：
    1. Study demonstrated orphan G-protein coupled receptor 110 (GPR110, ADGRF1) as the synaptamide receptor, mediating synaptamide-induced bioactivity in a cAMP-dependent manner. PMID: 27759003
    2. High GPR110 expression is associated with CRLF2-rearranged acute lymphoblastic leukemia. PMID: 28866095
    3. ADGRF1 single-nucleotide polymorphisms role in susceptibility to non-small cell lung cancer PMID: 28968839
    4. The results suggested the possible participation of STAT3 instead of ERK in the GPR110 signaling pathways and progression of glioma. PMID: 28728843
    5. GPR56 and GPR110 are activated by exposure of a cryptic tethered agonist PMID: 25918380
    6. GPR110 is an oncogene overexpressed in lung and prostate cancer PMID: 20149256

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  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.; [Isoform 2]: Secreted.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 組織特異性：
    Mainly expressed in the kidney. Up-regulated in lung adenocarcinomas and prostate cancers.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18990

    OMIM: 617430

    KEGG: hsa:266977

    STRING: 9606.ENSP00000360299

    UniGene: Hs.733762