GRID1 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9ULK0
基因名：

GRID1
別名：

GRID1 antibody; KIAA1220Glutamate receptor ionotropic antibody; delta-1 antibody; GluD1 antibody; GluR delta-1 subunit antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the C-terminal region of Human GluR-δ1.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應用范圍：

WB, IHC, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.
基因功能參考文獻：
1. GRID1 expression is downregulated in both MECP2- and CDKL5-mutated iPS cells and upregulated in neuronal precursors and mature neurons. PMID: 24916645
2. GRID1 genotype is related to gray matter variation in prefrontal and anterior thalamic brain areas in healthy subjects, but not in schizophrenia patients, indicating a potential role in thalamo-cortical functioning. PMID: 23017809
3. results strongly support previously reported association studies, implicating GRID1 in the etiology of schizophrenia PMID: 17490860
4. The results of this study suggested that genetic variants in the GRID1 transcriptional regulatory region may play a role in the etiology of schizophrenia. PMID: 19346103
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
蛋白家族：

Glutamate-gated ion channel (TC 1.A.10.1) family, GRID1 subfamily
數(shù)據(jù)庫鏈接：

HGNC: 4575

OMIM: 610659

KEGG: hsa:2894

STRING: 9606.ENSP00000330148

UniGene: Hs.530653