HAUS6 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q7Z4H7
基因名：

HAUS6
別名：

HAUS6 antibody; DGT6 antibody; FAM29A antibody; KIAA1574HAUS augmin-like complex subunit 6 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human FAM29A
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin.
基因功能參考文獻：
1. Hice1 and hDgt6 are core components of distinct augmin sub-complexes. PMID: 25173975
2. Results suggest that an important mitotic function for gamma-tubulin may lie within the spindle, where augmin (Dgt2-6; FAM29A) and gamma-tubulin function cooperatively to amplify the number of microtubules. PMID: 18443220
3. FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. PMID: 19029337
亞細胞定位：

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
蛋白家族：

HAUS6 family
數(shù)據(jù)庫鏈接：

HGNC: 25948

OMIM: 613433

KEGG: hsa:54801

STRING: 9606.ENSP00000369871

UniGene: Hs.533468