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  4. HMG20B Antibody

HMG20B Antibody

  • 中文名稱：
    HMG20B兔多克隆抗體
  • 貨號：
    CSB-PA010542GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    HMG20B
  • 別名：
    BRAF25 antibody; BRAF35 antibody; BRCA2 associated factor 35 antibody; BRCA2-associated factor 35 antibody; High Mobility Group Protein 20B antibody; HM20B_HUMAN antibody; HMG box containing protein 20B antibody; HMG box-containing protein 20B antibody; HMG domain-containing protein 2 antibody; HMG domain-containing protein HMGX2 antibody; HMG20B antibody; SMARCE1-related protein antibody; SMARCE1r antibody; sox like antibody; Sox like transcriptional factor antibody; Sox-like transcriptional factor antibody; SOXL antibody; Structural DNA binding protein BRAF35 antibody; Structural DNA-binding protein BRAF35 antibody; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human HMG20B
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
  • 基因功能參考文獻(xiàn)：
    1. Our data reveal a novel role for MID1 and for atypical ubiquitination in balancing BRAF35 presence, and likely its activity, within nuclear and cytoplasmic compartments PMID: 28760657
    2. Fresh insight into the mechanism by which the HMG20b-BRCA2 complex controls mitotic cell division, and implicate heterozygous HMG20b mutations affecting cytokinesis regulation in the genesis of human cancers. PMID: 25486196
    3. HMG20B/BRAF35 forms heterodimers with HMG20A/iBRAF. Heterodimerization impairs HMG20B/BRAF35 sumoylation and interaction with the LSD1-CoREST complex. PMID: 22570500
    4. a novel function for HMG20b in cytokinesis is regulated by its interaction with the BRC repeats of BRCA2 PMID: 21399666
    5. beta-dystrobrevin interacts with the HMG20 proteins iBRAF and BRAF35 PMID: 20530487
    6. molecular cloning, nucleotide and amino acid sequencing PMID: 11997092
    7. complex containing histone deacetylase complex containing histone deacetylase mediates repression of neuronal-specific genes. PMID: 12032298
    8. molecular Cloning of BRAF25, an alternatively spliced protein of BRAF35 PMID: 12083779
    9. Results demonstrating association of BRAF35 with KIF4 through the interaction of their respective alpha-helical coiled-coil domains is unique so far in mammals. PMID: 12809554
    10. we have examined Sox gene expression in 60 human primary gliomas. Transcripts from each of the six group E and group D genes were expressed in gliomas of various types and malignancy grades PMID: 17961134

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  • 亞細(xì)胞定位：
    Nucleus. Chromosome. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2.
  • 組織特異性：
    Ubiquitously expressed in adult tissues.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 5002

    OMIM: 605535

    KEGG: hsa:10362

    STRING: 9606.ENSP00000328269

    UniGene: Hs.406534