HNRNPR Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O43390
基因名：

HNRNPR
別名：

FLJ25714 antibody; Heterogeneous nuclear ribonucleoprotein R antibody; hnRNP R antibody; hnRNP-R antibody; HNRNPR antibody; HNRPR antibody; HNRPR_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human HNRNPR
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of ribonucleosomes, which are complexes of at least 20 other different heterogeneous nuclear ribonucleoproteins (hnRNP). hnRNP play an important role in processing of precursor mRNA in the nucleus.
基因功能參考文獻：
1. demonstrated that HNRNPR binds MHC class I mRNAs in their 3' untranslated regions and enhances their stability and their expression; regulation by HNRNPR modulates the cytotoxic activity of NK cell; conclude that HNRNPR acts as a general positive regulator of MHC class I expression PMID: 27194785
2. SMN is involved in the axonal translocation of hnRNP R and hnRNP R-bound RNA/protein complexes. PMID: 25338097
3. Data demonstrate that expression levels of hnRNP A1, Q, K, R, and U influence HIV-1 production by persistently infected astrocytes, linking these hnRNPs to HIV replication. PMID: 19808671
4. Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: HNRNPR. PMID: 19902070
5. HNRNPR enhanced transcription from the c-fos promoter. PMID: 19581295
6. validated occurrence of an unusual TG 3' splice site in intron 7 PMID: 17672918
顯示更多

收起更多
亞細胞定位：

Nucleus. Microsome. Nucleus, nucleoplasm. Cytoplasm.
數(shù)據(jù)庫鏈接：

HGNC: 5047

OMIM: 607201

KEGG: hsa:10236

STRING: 9606.ENSP00000363745

UniGene: Hs.373763