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  4. HOXA6 Antibody

HOXA6 Antibody

  • 中文名稱：
    HOXA6兔多克隆抗體
  • 貨號(hào)：
    CSB-PA002956
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of K562 cells using HoxA6 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    HOXA6
  • 別名：
    Homeo box 1B antibody; Homeo box A6 antibody; Homeobox 1B antibody; Homeobox A6 antibody; Homeobox protein Hox A6 antibody; Homeobox protein Hox-1B antibody; Homeobox protein Hox-A6 antibody; Homeobox protein HoxA6 antibody; HOX 1 antibody; Hox 1B antibody; HOX1 antibody; HOX1.2 antibody; Hox1B antibody; HOXA6 antibody; HX A6 antibody; HXA6 antibody; HXA6_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human HoxA6.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能參考文獻(xiàn)：
    1. Results demonstrated thatHOXA6 is up-regulated in colorectal cancer (CRC) and promoted cell proliferation, migration and invasion, but inhibited apoptosis, whereas the downregulated expression of HOXA6 produced the opposite effects. HOXA6 regulated apoptosis through the Bcl-2 signaling pathway, and regulated migration and invasion through the EMT process. PMID: 29620285
    2. HOXA6 is a signature gene involved in cell growth and sensitivity to chemotherapy in acute myeloid leukemia cells. PMID: 23539541
    3. Data indicate that genes with hypermethylated CpG islands in malignant meningiomas, such as HOXA6 and HOXA9, tend to coincide with the binding sites of polycomb repressive complexes (PRC) in early developmental stage. PMID: 23349797
    4. Enforced overexpression of HOXA6 or HOXA9 in FDCP-Mix resulted in increased proliferation and colony formation but had negligible effect on differentiation in early multipotential and later committed precursor cells PMID: 19157684
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Antp homeobox family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 5107

    OMIM: 142951

    KEGG: hsa:3203

    STRING: 9606.ENSP00000222728

    UniGene: Hs.679517