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  4. HRSP12 Antibody

HRSP12 Antibody

  • 中文名稱：
    HRSP12兔多克隆抗體
  • 貨號(hào)：
    CSB-PA010744GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    RIDA
  • 別名：
    14.5 kDa translational inhibitor protein antibody; 2-iminobutanoate/2-iminopropanoate deaminase antibody; Heat responsive protein 12 antibody; Heat-responsive protein 12 antibody; Hrsp12 antibody; p14.5 antibody; Perchloric acid soluble protein antibody; PSP antibody; Reactive intermediate imine deaminase A homolog antibody; Ribonuclease UK114 antibody; RIDA antibody; Translational inhibitor p14.5 antibody; Translational inhibitor protein p14.5 antibody; UK114 antibody; UK114 antigen homolog antibody; UK114_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human HRSP12
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.; Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex. Acts by bridging YTHDF2 and the ribonuclease P/MRP complex. RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage.
  • 基因功能參考文獻(xiàn)：
    1. x-ray crystallography study of p14.5 PMID: 14997576
    2. analysis of ligand binding sites of protein p14.5 PMID: 16198412
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Peroxisome. Mitochondrion.
  • 蛋白家族：
    RutC family
  • 組織特異性：
    Expressed predominantly in liver and kidney. Lower levels in lung and brain.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16897

    OMIM: 602487

    KEGG: hsa:10247

    STRING: 9606.ENSP00000254878

    UniGene: Hs.18426