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IFT172 Antibody, Biotin conjugated

  • 中文名稱(chēng)：
    IFT172兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA887019LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) IFT172 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    IFT172
  • 別名：
    IF172_HUMAN antibody; ift172 antibody; Intraflagellar transport 172 homolog (Chlamydomonas) antibody; Intraflagellar transport protein 172 homolog antibody; Osm 1 antibody; Selective LIM binding factor homolog antibody; SLB antibody; Wim antibody; Wimple homolog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Intraflagellar transport protein 172 homolog protein (1368-1502AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
  • 基因功能參考文獻(xiàn)：
    1. This is the second report of IFT172 mutations in BBS patients validating IFT172 as the twentieth BBS gene (BBS20). PMID: 26763875
    2. Findings identified mutations in IFT172 that lead to a recessive form of non-syndromic retinitis pigmentosa and Bardet-Biedl syndrome and suggest that the primary IFT172 mutations alone are not sufficient to explain the wide range of phenotypes. PMID: 25168386
    3. We have identified defects in IFT172 as a cause of complex asphyxiating thoracic dystrophy and Mainzer-Saldino syndrome. PMID: 24140113
  • 相關(guān)疾?。?/div>
    Short-rib thoracic dysplasia 10 with or without polydactyly (SRTD10); Retinitis pigmentosa 71 (RP71)
  • 亞細(xì)胞定位：
    Cell projection, cilium. Note=Localized to the axoneme and around the base of the cilium.
  • 蛋白家族：
    IFT172 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30391

    OMIM: 607386

    KEGG: hsa:26160

    STRING: 9606.ENSP00000260570

    UniGene: Hs.127401