IL17RE Antibody

說(shuō)明書

產(chǎn)品詳情

Uniprot No.：

Q8NFR9
基因名：

IL17RE
別名：

IL17RE antibody; UNQ3056/PRO9877 antibody; Interleukin-17 receptor E antibody; IL-17 receptor E antibody; IL-17RE antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Human IL17RE
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.
基因功能參考文獻(xiàn)：
1. IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens. PMID: 21993849
亞細(xì)胞定位：

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Secreted.; [Isoform 4]: Cytoplasm.; [Isoform 5]: Secreted.
組織特異性：

Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 18439

OMIM: 614995

KEGG: hsa:132014

STRING: 9606.ENSP00000295980

UniGene: Hs.390823