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JRK Antibody, HRP conjugated

  • 中文名稱：
    JRK兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA525639NB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) JRK Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    JRK
  • 別名：
    JRK antibody; JH8 antibody; Jerky protein homolog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Peptide sequence from Human Jerky protein homolog protein (465-483AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May bind DNA.
  • 基因功能參考文獻(xiàn)：
    1. JRK expression was aberrantly elevated in 21% of colorectal cancers, 15% of breast and ovarian cancers and was associated with increased expression of beta-catenin target genes and increased cell proliferation PMID: 26455321
    2. in the adult intestine, Ebd acts independently of Ewg in physiological Wnt signaling, but cooperates with Ewg to induce the hyperactivation of Wnt target gene expression following Apc1 loss. These findings have relevance for human tumorigenesis, as Jerky (JRK/JH8), the human Ebd homolog, promotes Wnt pathway hyperactivation and is overexpressed in colorectal, breast, and ovarian cancers PMID: 28708826
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Tigger transposable element derived protein family
  • 組織特異性：
    Expressed ubiquitously.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 6199

    OMIM: 603210

    KEGG: hsa:8629

    UniGene: Hs.535903