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  4. KBTBD6 Antibody

KBTBD6 Antibody

  • 中文名稱：
    KBTBD6兔多克隆抗體
  • 貨號：
    CSB-PA774812LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate
      All lanes: KBTBD6 antibody at 3.4µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 77 kDa
      Observed band size: 77 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA774812LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA774812LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) KBTBD6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KBTBD6
  • 別名：
    KBTB6_HUMAN antibody; KBTBD6 antibody; Kelch repeat and BTB (POZ) domain containing 6 antibody; Kelch repeat and BTB domain-containing protein 6 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Kelch repeat and BTB domain-containing protein 6 protein (1-139AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，KBTBD6 Antibody (CSB-PA774812LA01HU)，的標(biāo)記方式是Non-conjugated。對于KBTBD6 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA774812LB01HU KBTBD6 Antibody, HRP conjugated ELISA
    FITC CSB-PA774812LC01HU KBTBD6 Antibody, FITC conjugated
    Biotin CSB-PA774812LD01HU KBTBD6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    As part of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex functions as a substrate adapter for the RAC1 guanine exchange factor (GEF) TIAM1, mediating its 'Lys-48' ubiquitination and proteasomal degradation. By controlling this ubiquitination, regulates RAC1 signal transduction and downstream biological processes including the organization of the cytoskeleton, cell migration and cell proliferation. Ubiquitination of TIAM1 requires the membrane-associated protein GABARAP which may restrict locally the activity of the complex.
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25340

    OMIM: 617738

    KEGG: hsa:89890

    STRING: 9606.ENSP00000368799

    UniGene: Hs.534040