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KCNH6 Antibody

  • 中文名稱：
    KCNH6兔多克隆抗體
  • 貨號：
    CSB-PA449173
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA449173(KCNH6 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hepg2 cells, HT29 cells, Primary antibody: CSB-PA449173(KCNH6 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    KCNH6
  • 別名：
    KCNH6 antibody; ERG2 antibody; Potassium voltage-gated channel subfamily H member 6 antibody; Ether-a-go-go-related gene potassium channel 2 antibody; ERG-2 antibody; Eag-related protein 2 antibody; Ether-a-go-go-related protein 2 antibody; hERG-2 antibody; hERG2 antibody; Voltage-gated potassium channel subunit Kv11.2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Rat
  • 免疫原：
    Fusion protein of Human KCNH6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:35-1:150
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current. Channel properties may be modulated by cAMP and subunit assembly.
  • 基因功能參考文獻：
    1. results indicated that downregulation of miR-224 suppressed cell growth and resulted in the enhancement of cell apoptosis through activation of the ERG2-BAK-induced apoptosis pathway PMID: 25783051
    2. Transcripts for HERG1 were present in all adenomas and although transcripts for HERG2 and HERG3 were also detected, their expression level was more variable. PMID: 12634931
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.2/KCNH6 sub-subfamily
  • 組織特異性：
    Expressed in prolactin-secreting adenomas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18862

    OMIM: 608168

    KEGG: hsa:81033

    STRING: 9606.ENSP00000463533

    UniGene: Hs.591177