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KHDRBS2 Antibody

  • 中文名稱：
    KHDRBS2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA730139LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: KHDRBS2 antibody at 7µg/ml
      Lane 1: K562 whole cell lysate
      Lane 2: Hela whole cell lysate
      Lane 3: A431 whole cell lysate
      Lane 4: Jurkat whole cell lysate
      Lane 5: NIH/3T3 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 39 kDa
      Observed band size: 39 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA730139LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) KHDRBS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KHDRBS2
  • 別名：
    KH domain containing; RNA binding; signal transduction associated protein 2 antibody; 6330586C16Rik antibody; bA535F17.1 antibody; FLJ38664 antibody; hSLM 1 antibody; hSLM-1 antibody; KH domain containing; RNA binding; signal transduction associated 2 antibody; KH domain-containing antibody; KHDR2_HUMAN antibody; khdrbs2 antibody; MGC26664 antibody; RNA-binding antibody; Sam68 like mammalian protein 1 antibody; Sam68-like mammalian protein 1 antibody; signal transduction-associated protein 2 antibody; SLM 1 antibody; SLM-1 antibody; SLM1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein (1-349AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，KHDRBS2 Antibody (CSB-PA730139LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于KHDRBS2 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA730139LB01HU KHDRBS2 Antibody, HRP conjugated ELISA
    FITC CSB-PA730139LC01HU KHDRBS2 Antibody, FITC conjugated
    Biotin CSB-PA730139LD01HU KHDRBS2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.
  • 基因功能參考文獻(xiàn)：
    1. molecular cloning and characterization PMID: 12549823
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    KHDRBS family
  • 組織特異性：
    Highly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 18114

    OMIM: 610487

    KEGG: hsa:202559

    STRING: 9606.ENSP00000281156

    UniGene: Hs.519794