KIF21B Antibody, Biotin conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) KIF21B Polyclonal antibody
Uniprot No.：

O75037
基因名：

KIF21B
別名：

KI21B_HUMAN antibody; KIAA0449 antibody; KIF21B antibody; Kinesin-like protein KIF21B antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Kinesin-like protein KIF21B protein (829-986AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface.
基因功能參考文獻：
1. Thus, KIF21B combines microtubule-binding and regulatory activities that together constitute an autonomous microtubule pausing factor. PMID: 28290984
2. KIF21B is associated with ankylosing spondylitis in a Chinese population of Shandong Province PMID: 25149646
3. KIF21B may play an important role in the pathogenesis of AS in the Chinese population and might be a new therapeutic target for AS. PMID: 24065353
4. Data show the association of SNPs in KIF21B with multiple sclerosis in a Belgian study population. PMID: 20587413
5. Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B as susceptibility loci PMID: 20007504
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亞細胞定位：

Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, growth cone. Cell projection, axon. Cytoplasmic vesicle.
蛋白家族：

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
數(shù)據(jù)庫鏈接：

HGNC: 29442

OMIM: 608322

KEGG: hsa:23046

STRING: 9606.ENSP00000328494

UniGene: Hs.169182