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KRT71 Antibody, HRP conjugated

  • 中文名稱：
    KRT71兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA660951LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) KRT71 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KRT71
  • 別名：
    CK-71 antibody; Cytokeratin-71 antibody; hK6irs antibody; hK6irs1 antibody; K2C71_HUMAN antibody; K6IRS1 antibody; K71 antibody; KB34 antibody; Keratin 6 irs antibody; Keratin 6, inner root sheath, 1 antibody; Keratin antibody; keratin, type II cytoskeletal 71 antibody; Keratin-71 antibody; KRT6IRS antibody; KRT6IRS1 antibody; KRT71 antibody; MGC119390 antibody; MGC119391 antibody; OTTHUMP00000236990 antibody; type II cytoskeletal 71 antibody; Type II inner root sheath-specific keratin-K6irs1 antibody; Type-II keratin Kb34 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Keratin, type II cytoskeletal 71 protein (201-500AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.
  • 基因功能參考文獻(xiàn)：
    1. Demonstration of the heterozygous mutation c.422T>G (p.Phe141Cys) within the helix initiation motif of the inner root sheath-specific keratin K71 (KRT71) gene in affected family members with autosomal dominant woolly hair/hypotrichosis. PMID: 22592156
    2. A novel epithelial keratin, hK6irs1, is expressed differentially in all layers of the inner root sheath, including specialized huxley cells (Flugelzellen) of the human hair follicle.(HK6IRS1) PMID: 11982755
  • 相關(guān)疾?。?/div>
    Hypotrichosis 13 (HYPT13)
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Intermediate filament family
  • 組織特異性：
    Highly expressed in hair follicles from scalp. Specifically expressed in the inner root sheath (IRS) of the hair follicle. Present in the all 3 IRS layers: the cuticle, the Henle and the Huxley layers. Also detected in the pseudopods of specialized Huxley
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 28927

    OMIM: 608245

    KEGG: hsa:112802

    STRING: 9606.ENSP00000267119

    UniGene: Hs.660007