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  4. LMOD1 Antibody

LMOD1 Antibody

  • 中文名稱：
    LMOD1兔多克隆抗體
  • 貨號：
    CSB-PA013013GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    LMOD1
  • 別名：
    1D antibody; 64 kDa autoantigen 1D antibody; 64 kDa autoantigen 1D3 antibody; 64 kDa autoantigen D1 antibody; 9530015K06Rik antibody; D1 antibody; Leiomodin antibody; Leiomodin-1 antibody; Lmod1 antibody; LMOD1_HUMAN antibody; muscle form antibody; SM LMOD antibody; SM-Lmod antibody; SMLMOD antibody; Smooth muscle leiomodin antibody; Thyroid associated ophthalmopathy autoantigen antibody; Thyroid-associated ophthalmopathy autoantigen antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human LMOD1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Mediates nucleation of actin filaments.
  • 基因功能參考文獻：
    1. Loss of LMOD1 results in a reduction of filamentous actin, elongated cytoskeletal dense bodies, and impaired intestinal smooth muscle contractility. PMID: 28292896
    2. Key role for miR-214 in modulation of MEF2C-MYOCD-LMOD1 signaling. PMID: 27144530
    3. Lmod1 is a new SMC-restricted SRF/MYOCD target gene. PMID: 22157009
    4. Lmod1 is a component of the smooth muscle contractile apparatus extractable by high salt, not a transmembrane protein as previously predicted. PMID: 11350761
    5. Lmod1, formerly the 64kD human autoantigen D1, is expressed in smooth muscle and striated extraocular slow muscle fibers, colocalized with myosin in the contractile apparatus. Protein levels are unaltered by hyperthyroidism. PMID: 10520227
    6. Lmod1 is a member of the Tropomodulin family of actin binding proteins, and is most highly expressed in smooth muscle. PMID: 11318603

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  • 亞細胞定位：
    Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tropomodulin family
  • 組織特異性：
    Detected in lung vascular smooth muscle (at protein level). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle. Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6647

    OMIM: 602715

    KEGG: hsa:25802

    STRING: 9606.ENSP00000356257

    UniGene: Hs.519075