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  4. Ly6e Antibody

Ly6e Antibody

  • 中文名稱：
    Ly6e兔多克隆抗體
  • 貨號：
    CSB-PA717533LA01MO
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: Ly6e antibody at 8µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 14 kDa
      Observed band size: 14 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Mus musculus (Mouse) Ly6e Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Ly6e antibody; Ly67 antibody; Sca-2 antibody; Tsa-1Lymphocyte antigen 6E antibody; Ly-6E antibody; Stem cell antigen 2 antibody; Thymic shared antigen 1 antibody; TSA-1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Mouse, Human
  • 免疫原：
    Recombinant Mouse Lymphocyte antigen 6E protein (21-102AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，Ly6e Antibody (CSB-PA717533LA01MO)，的標記方式是Non-conjugated。對于Ly6e Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA717533LB01MO Ly6e Antibody, HRP conjugated ELISA
    FITC CSB-PA717533LC01MO Ly6e Antibody, FITC conjugated
    Biotin CSB-PA717533LD01MO Ly6e Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of murine coronavirus, mouse hepatitis virus, by interfering with spike protein-mediated membrane fusion. Plays also an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response.
  • 基因功能參考文獻：
    1. Knocking down Ly6e greatly reduced SynA-induced cell fusion, thus suggesting that Ly6e is the sole receptor for SynA in vivo. PMID: 28679758
    2. Sca-2 -- a signal transducer situated at the nexus of surface molecules regulating death receptor-mediated apoptosis in hepatoma PMID: 15170814
  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 組織特異性：
    Ubiquitously expressed in mouse adult tissues with maximal expression in the lung and the salivary gland. Expression is strikingly lower in the fetal tissues except for the placenta. Present in thymus where its expression is observed in immature thymocyte
  • 數(shù)據(jù)庫鏈接：

    KEGG: mmu:17069

    STRING: 10090.ENSMUSP00000056703

    UniGene: Mm.788