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  4. MAB21L2 Antibody, Biotin conjugated

MAB21L2 Antibody, Biotin conjugated

  • 中文名稱：
    MAB21L2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA896901LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MAB21L2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MAB21L2
  • 別名：
    MAB21L2 antibody; Protein mab-21-like 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein mab-21-like 2 protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Required for several aspects of embryonic development including normal development of the eye.
  • 基因功能參考文獻：
    1. mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. [review] PMID: 27558071
    2. The two unrelated individuals with a novel oculo-skeletal syndrome with intellectual disability described are heterozygous carriers of the same de novo missense mutation c.151C > T (p.Arg51Cys) in MAB21L2. PMID: 26116559
    3. These findings support the identification of MAB21L2 as a novel factor involved in human coloboma and highlight the power of genome editing manipulation in model organisms for analysis of the effects of whole exome variation in humans. PMID: 25719200
    4. This report provides compelling human genomic and genetic evidence that mutations in MAB21L2 cause major eye malformations. PMID: 24906020
  • 相關疾病：
    Microphthalmia/coloboma and skeletal dysplasia syndrome (MCSKS)
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Mab-21 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6758

    OMIM: 604357

    KEGG: hsa:10586

    STRING: 9606.ENSP00000324701

    UniGene: Hs.584852