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MARVELD3 Antibody

  • 中文名稱：
    MARVELD3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA842633LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of Hela cells with CSB-PA842633LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MARVELD3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MARVELD3
  • 別名：
    MARVELD3; MRVLDC3; MARVEL domain-containing protein 3
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human MARVEL domain-containing protein 3 protein (1-189AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，MARVELD3 Antibody (CSB-PA842633LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于MARVELD3 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA842633LB01HU MARVELD3 Antibody, HRP conjugated ELISA
    FITC CSB-PA842633LC01HU MARVELD3 Antibody, FITC conjugated
    Biotin CSB-PA842633LD01HU MARVELD3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    As a component of tight junctions, plays a role in paracellular ion conductivity.
  • 基因功能參考文獻(xiàn)：
    1. MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. PMID: 24567356
    2. MarvelD3 is transcriptionally downregulated in Snail-induced epithelial-mesenchymal transition during the progression for the pancreatic cancer. PMID: 21763689
    3. marvelD3, occludin, and tricellulin define the tight junction-associated MARVEL protein family PMID: 20164257
    4. MarvelD3 co-localises with occludin at tight junctions in intestinal and corneal epithelial cells. PMID: 20028514
  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein. Cell junction, tight junction.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30525

    OMIM: 614094

    KEGG: hsa:91862

    UniGene: Hs.513706