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MAST1 Antibody

  • 中文名稱：
    MAST1兔多克隆抗體
  • 貨號：
    CSB-PA897529LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA897529LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA897529LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA897529LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    MAST1 polyclonal antibody CSB-PA897529LA01HU was produced in the rabbit immunized by using the Recombinant Human Microtubule-associated serine/threonine-protein kinase 1 protein (687-879AA) as the immunogen. The target protein MAST1 is essential for correct brain development, and appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Diseases associated with MAST1 include Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations and Cerebellar Hypoplasia.
    This Rabbit anti-Homo sapiens (Human) MAST1 Polyclonal antibody was tested in the ELISA, IHC and IF applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the MAST1 proteins of human-origin and may be used to detect the endogenous levels of MAST1 protein.
  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MAST1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MAST1
  • 別名：
    9430008B02Rik antibody; KIAA0973 antibody; MAST 1 antibody; MAST1 antibody; MAST1_HUMAN antibody; Microtubule associated serine/threonine kinase 1 antibody; Microtubule associated serine/threonine protein kinase 1 antibody; Microtubule-associated serine/threonine-protein kinase 1 antibody; SAST 124 antibody; SAST 170 antibody; SAST antibody; SAST170 antibody; Syntrophin associated serine/threonine kinase antibody; Syntrophin associated serine/threonine protein kinase antibody; Syntrophin-associated serine/threonine-protein kinase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Microtubule-associated serine/threonine-protein kinase 1 protein (687-879AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，MAST1 Antibody (CSB-PA897529LA01HU)，的標(biāo)記方式是Non-conjugated。對于MAST1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA897529LB01HU MAST1 Antibody, HRP conjugated ELISA
    FITC CSB-PA897529LC01HU MAST1 Antibody, FITC conjugated
    Biotin CSB-PA897529LD01HU MAST1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Microtubule-associated protein essential for correct brain development. Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.
  • 基因功能參考文獻：
    1. Overexpression of MAST1 or MAST2 gene fusions has a proliferative effect both in vitro and in vivo in breast cancer cell lines. PMID: 22101766
    2. Discusses cloning of Sast, the mouse ortholog of human MAST1. PMID: 10404183
    3. Discusses cloning of Sast124, the rat ortholog of MAST1. PMID: 12614677
  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family
  • 組織特異性：
    Expressed in fetal brain.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19034

    OMIM: 612256

    KEGG: hsa:22983

    STRING: 9606.ENSP00000251472

    UniGene: Hs.227489