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  4. MCIDAS Antibody, Biotin conjugated

MCIDAS Antibody, Biotin conjugated

  • 中文名稱：
    MCIDAS兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA518689LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MCIDAS Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MCIDAS
  • 別名：
    IDAS antibody; Mci antibody; MCI_HUMAN antibody; Multicilin antibody; Protein Idas antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Multicilin protein (3-110AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1.
  • 基因功能參考文獻(xiàn)：
    1. MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia.MCIDAS regulates CCNO and FOXJ1 expression. PMID: 25048963
    2. The properties of the Idas-Geminin complex suggest it as the functional form of Idas and provide a possible mechanism to modulate Geminin activity PMID: 24064211
    3. Idas as a novel Geminin binding partner, implicated in cell cycle progression, and a putative regulator of proliferation-differentiation decisions during development. PMID: 21543332
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Geminin family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 40050

    OMIM: 614086

    KEGG: hsa:345643

    STRING: 9606.ENSP00000426359

    UniGene: Hs.394578