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MDH2 Antibody

  • 中文名稱:
    MDH2兔多克隆抗體
  • 貨號(hào):
    CSB-PA013623ESR2HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: MDH2 antibody at 4µg/ml
      Lane 1: Mouse lung tissue
      Lane 2: 293T whole cell lysate
      Lane 3: K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 36, 31 kDa
      Observed band size: 36 kDa
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) MDH2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MDH2
  • 別名:
    M MDH antibody; Malate dehydrogenase 2; NAD (mitochondrial) antibody; Malate dehydrogenase antibody; Malate dehydrogenase; mitochondrial antibody; MDH antibody; mdh2 antibody; MDHM_HUMAN antibody; MGC:3559 antibody; mitochondrial antibody; Mitochondrial malate dehydrogenase 2; NAD antibody; Mor 1 antibody; MOR1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Malate dehydrogenase, mitochondrial protein (59-338AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn):
    1. these data suggest that MDH2, functioning as an RNA-binding protein, is involved in the posttranscriptional downregulation of SCN1A expression under seizure condition. PMID: 28433711
    2. loss-of-function mutations in MDH2 are also associated with severe neurological clinical presentations in children PMID: 27989324
    3. Data indicate that acetyl-CoA acetyltransferase (ACAT1) and malate dehydrogenase (MDH2) are involved in various drug-resistance-forming mechanisms. PMID: 25639359
    4. Segregation of the mutation with disease and absence of MDH2 in mutated tumors revealed MDH2 as a novel pheochromocytoma/paraganglioma susceptibility gene. PMID: 25766404
    5. L-2-hydroxyglutarate accumulates as a result of a deficiency in FAD-linked L-2-hydroxyglutarate dehydrogenase. mitochondrial L-malate dehydrogenase is responsible for the excretion of L-2-hydroxyglutarate in this condition. PMID: 17603759

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  • 相關(guān)疾?。?/div>
    Epileptic encephalopathy, early infantile, 51 (EIEE51)
  • 亞細(xì)胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    LDH/MDH superfamily, MDH type 1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 6971

    OMIM: 154100

    KEGG: hsa:4191

    STRING: 9606.ENSP00000327070

    UniGene: Hs.520967