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  4. MED18 Antibody, FITC conjugated

MED18 Antibody, FITC conjugated

  • 中文名稱：
    MED18兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA871577LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MED18 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MED18
  • 別名：
    FLJ20045 antibody; hMED 18 antibody; hMED18 antibody; Human Mediator of RNA Polymerase II Transcription antibody; MED 18 antibody; med18 antibody; MED18_HUMAN antibody; Mediator complex subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 homolog antibody; OTTHUMP00000003645 antibody; p28b antibody; TRAP/mediator complex subunit p28b antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Mediator of RNA polymerase II transcription subunit 18 protein (35-208AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • 基因功能參考文獻：
    1. A novel transcriptional repression mechanism of hMED18 mediated by hCDK8 and further a novel positive role of free CDK/cyclin module in transcriptional activation is described. PMID: 24840924
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Mediator complex subunit 18 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25944

    OMIM: 612384

    KEGG: hsa:54797

    STRING: 9606.ENSP00000362948

    UniGene: Hs.479911