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  4. MOBP Antibody, FITC conjugated

MOBP Antibody, FITC conjugated

  • 中文名稱：
    MOBP兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA014701LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MOBP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MOBP
  • 別名：
    MOBP antibody; Myelin-associated oligodendrocyte basic protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Myelin-associated oligodendrocyte basic protein (1-81AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
  • 基因功能參考文獻(xiàn)：
    1. Mutation in MOBP gene is associated with amyotrophic lateral sclerosis. PMID: 27455348
    2. rs1768208 is associated with corticobasal degeneration. PMID: 26077951
    3. The rs1768208 risk polymorphism in MOBP has prognostic value in behavioral-variant frontotemporal dementia. PMID: 24994843
    4. Genotypes at MOBP and EIF2AK3 confer risk predominantly in APOE epsilon4-positive subjects, with indications of an interaction between APOE and MOBP or EIF2AK3 on Alzheimer's disease risk. PMID: 23116876
    5. MOBP mRNA levels were increased in the DLPFC white matter in patients with a history of substance abuse. PMID: 17964117

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  • 亞細(xì)胞定位：
    Cytoplasm, perinuclear region.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 7189

    OMIM: 600948

    KEGG: hsa:4336

    UniGene: Hs.121333