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MOV10L1 Antibody, Biotin conjugated

  • 中文名稱：
    MOV10L1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA871604LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MOV10L1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MOV10L1
  • 別名：
    Cardiac helicase activated by MEF2 protein antibody; Cardiac specific RNA helicase antibody; CHAMP antibody; Csm antibody; M10L1_HUMAN antibody; Moloney leukemia virus 10 like protein 1 antibody; Moloney leukemia virus 10-like protein 1 antibody; MOV10 like 1 antibody; MOV10 like protein 1 antibody; MOV10-like protein 1 antibody; MOV10L1 antibody; Mov10l1; Moloney leukemia virus 10 like 1; homolog (mouse) antibody; Putative helicase Mov10l1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human RNA helicase Mov10l1 protein (336-425AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.
  • 基因功能參考文獻(xiàn)：
    1. Our results suggest that MOV10L1 gene polymorphisms in the studied infertile males with complete maturation arrest are linked to infertility. PMID: 24817005
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    DNA2/NAM7 helicase family, SDE3 subfamily
  • 組織特異性：
    [Isoform 1]: Specifically expressed in testis.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 7201

    OMIM: 605794

    KEGG: hsa:54456

    STRING: 9606.ENSP00000262794

    UniGene: Hs.62880