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MRPS18B Antibody

  • 中文名稱：
    MRPS18B兔多克隆抗體
  • 貨號(hào)：
    CSB-PA014892GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MRPS18B
  • 別名：
    28S ribosomal protein S18-2 antibody; 28S ribosomal protein S18b antibody; 28S ribosomal protein S18b; mitochondrial antibody; C6orf14 antibody; DKFZp564H0223 antibody; HSPC 183 antibody; HSPC183 antibody; mitochondrial antibody; Mitochondrial ribosomal protein S18 2 antibody; Mitochondrial ribosomal protein S18B antibody; MRP S18 2 antibody; MRP S18 b antibody; MRP S18b antibody; MRP-S18-2 antibody; MRP-S18-b antibody; MRPS 18B antibody; MRPS18 2 antibody; Mrps18-b antibody; MRPS18B antibody; PTD017 antibody; RT18B_HUMAN antibody; S18amt antibody; S18mt-b antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human MRPS18B
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. Together, these data suggest that the S18-2 protein induces epithelial to mesenchymal cell transition through the TWIST2/E-cadherin signalling and, consequently, CXCR4-mediated migration of prostate cancer cells. PMID: 29396484
    2. Evolutionary trace analysis showed that the S18-2 protein is mutated at the higher rate in tumors, compared with S18-1 and S18-3. The one of the most conserved residues in the S18-2 protein sequence, Gly132, is often mutated in colorectal cancer. PMID: 27489352
    3. We conclude that high expression of S18-2 and free E2F...1might be a good set of prognostic markers for endometrial cancer PMID: 26959119
    4. Studies suggest that mitochondrial ribosomal protein S18-2 protein, together with the retinoblastoma protein (RB), plays a crucial role in the control on cell stemness and differentiation. PMID: 28361860
    5. S18-2 is a newly identified oncoprotein that may be involved in cancerogenesis PMID: 26023799
    6. EBNA-6 {ebna-3c} binds to MRPS18-2 , and targets it to the nucleus; binding targets the small pocket of pRb, which is a site of interaction with E2F1. The MRPS18-2 competes with the binding of E2F1 to pRb, thereby raising the level of free E2F1 PMID: 18391203

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  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    Bacterial ribosomal protein bS18 family, Mitochondrion-specific ribosomal protein mS40 subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 14516

    OMIM: 611982

    KEGG: hsa:28973

    STRING: 9606.ENSP00000259873

    UniGene: Hs.655329