MSC Antibody, FITC conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) MSC Polyclonal antibody
Uniprot No.：

O60682
基因名：

MSC
別名：

ABF-1 antibody; ABF1 antibody; Activated B cell factor 1 antibody; Activated B-cell factor 1 antibody; bHLHa22 antibody; Class A basic helix-loop-helix protein 22 antibody; Msc antibody; MUSC_HUMAN antibody; Musculin antibody; MYOR antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Musculin protein (3-143AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.
基因功能參考文獻(xiàn)：
1. this study shows that musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity PMID: 28612433
2. results demonstrate that ABF-1 facilitates formation of memory B cells but prevents plasma cell differentiation. PMID: 25070843
3. role in repressing lymphotoxin alpha PMID: 15052269
4. ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma. PMID: 18368067
亞細(xì)胞定位：

Nucleus.
組織特異性：

Expressed in lymphoid tissues, B-cell lines and activated B-cells.
數(shù)據(jù)庫鏈接：

HGNC: 7321

OMIM: 603628

KEGG: hsa:9242

STRING: 9606.ENSP00000321445

UniGene: Hs.442619