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MSTO1 Antibody, FITC conjugated

  • 中文名稱：
    MSTO1兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA880106LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MSTO1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MSTO1
  • 別名：
    MSTO1 antibody; LST005 antibody; SLTP005 antibody; Protein misato homolog 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein misato homolog 1 protein (1-280AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in the regulation of mitochondrial distribution and morphology. Required for mitochondrial fusion and mitochondrial network formation.
  • 基因功能參考文獻(xiàn)：
    1. we have described two unrelated patients with biallelic MSTO1 mutations. Our report provides valuable information on the consequences of MSTO1 mutations for human phenotypes. PMID: 29339779
    2. Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxia PMID: 28544275
    3. Thus, an MSTO1 loss-of-function mutation is associated with a human disorder showing mitochondrial involvement. MSTO1 likely has a physiologically relevant role in mitochondrial morphogenesis by supporting mitochondrial fusion. PMID: 28554942
    4. These results indicated that human Misato has a role(s) in mitochondrial distribution and morphology and that its unregulated expression leads to cell death. PMID: 17349998
  • 相關(guān)疾病：
    Myopathy, mitochondrial, and ataxia (MMYAT)
  • 亞細(xì)胞定位：
    Mitochondrion outer membrane. Cytoplasm.
  • 蛋白家族：
    Misato family
  • 組織特異性：
    Present in all cell lines tested (at protein level). Widely expressed.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29678

    OMIM: 617619

    KEGG: hsa:55154

    UniGene: Hs.656547