MTX1 Antibody

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) MTX1 Polyclonal antibody
Uniprot No.：

Q13505
基因名：

MTX1
別名：

MTX1; MTX; MTXN; Metaxin-1; Mitochondrial outer membrane import complex protein 1
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Metaxin-1 protein (217-466AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in transport of proteins into the mitochondrion. Essential for embryonic development.
基因功能參考文獻：
1. after the induction of apoptosis, Bak switches from its association with Mtx2 and VDAC2 to a closer association with Mtx1. PMID: 27845183
2. Results describe the association between the MTX1 and beta-glucocerebrosidase genes and its possible effect on Parkinson disease. PMID: 21837367
3. Single Nucleotide Polymorphism in metaxin 1 is associated with Gaucher disease PMID: 15024629
4. The pathway of Voltage-dependent anion-selective channel biogenesis in human mitochondria involves the TOM complex, Sam50 and metaxins, and that it is evolutionarily conserved. PMID: 17510655
5. mitofilin helps regulate mitochondrial morphology and at least four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import PMID: 17624330
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亞細胞定位：

Membrane; Single-pass type I membrane protein. Mitochondrion outer membrane.
蛋白家族：

Metaxin family
數(shù)據(jù)庫鏈接：

HGNC: 7504

OMIM: 600605

KEGG: hsa:4580

STRING: 9606.ENSP00000357360

UniGene: Hs.490874