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  4. MYBL1 Antibody

MYBL1 Antibody

  • 中文名稱：
    MYBL1兔多克隆抗體
  • 貨號：
    CSB-PA010296
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MYBL1
  • 別名：
    A-Myb antibody; AMYB antibody; MGC120059 antibody; MGC120061 antibody; Myb related protein A antibody; Myb-like protein 1 antibody; Myb-related protein A antibody; MYBA_HUMAN antibody; MYBL1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human A-Myb.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Transcriptional activator of SOX30.
  • 基因功能參考文獻：
    1. Low MYBL1 expression is associated with colon cancer. PMID: 28096468
    2. Our study defines new molecular subclasses of ACC characterized by MYBL1 rearrangements and 5'-NFIB gene fusions. PMID: 26631609
    3. Thus, the LIMD1-MYBL1 Index had considerable clinical value for DLBCL subtype classification and prognosis. PMID: 25940947
    4. analysis of genetic alterations in MYBL1 in diffuse pediatric low-grade gliomas PMID: 23633565
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 7547

    OMIM: 159405

    KEGG: hsa:4603

    STRING: 9606.ENSP00000429633

    UniGene: Hs.445898