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NABP1 Antibody

  • 中文名稱：
    NABP1兔多克隆抗體
  • 貨號：
    CSB-PA016249GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    NABP1
  • 別名：
    FLJ13624 antibody; FLJ22833 antibody; hSSB2 antibody; MGC111163 antibody; Nabp1 antibody; Nucleic acid-binding protein 1 antibody; OBFC2A antibody; Oligonucleotide/oligosaccharide binding fold containing 2A antibody; Oligonucleotide/oligosaccharide binding fold containing protein 2A antibody; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A antibody; Sensor of single strand DNA complex subunit B2 antibody; Sensor of single-strand DNA complex subunit B2 antibody; Sensor of ssDNA subunit B2 antibody; Single stranded DNA binding protein 2 antibody; Single-stranded DNA-binding protein 2 antibody; SOSB2_HUMAN antibody; SOSS B2 antibody; SOSS complex subunit B2 antibody; SOSS-B2 antibody; SSB2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human OBFC2A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
  • 基因功能參考文獻(xiàn)：
    1. SNPs rs11903757, with closest proximity to NABP1 and SDPR, and rs966423 in DIRC3, were associated with survival in laryngeal squamous cell carcinoma patients. PMID: 27793000
    2. hSSB1 and hSSB2 form two separate complexes with similar structures, and both complexes participate in DNA damage response. PMID: 19605351
  • 亞細(xì)胞定位：
    Nucleus. Note=Localizes to nuclear foci following DNA damage.
  • 蛋白家族：
    SOSS-B family, SOSS-B2 subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26232

    OMIM: 612103

    KEGG: hsa:64859

    STRING: 9606.ENSP00000403683

    UniGene: Hs.591610