NAV1 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q8NEY1
基因名：

NAV1
別名：

NAV1 antibody; KIAA1151 antibody; KIAA1213 antibody; POMFIL3 antibody; STEERIN1Neuron navigator 1 antibody; Pore membrane and/or filament-interacting-like protein 3 antibody; Steerin-1 antibody; Unc-53 homolog 1 antibody; unc53H1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human NAV1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in neuronal migration.
基因功能參考文獻：
1. The +TIP Navigator 1 (NAV1) is important for neurite outgrowth and interacts and colocalizes with TRIO, a Rho guanine nucleotide exchange factor that enables neurite outgrowth by activating the Rho GTPases Rac1 and RhoG. PMID: 25065758
2. NAV1 forms a complex with the RhoGEF TRIO and the +TIP EB1 on the plus ends of growing microtubules, and regulates TRIO-mediated Rac1 activation and neurite outgrowth. PMID: 25065758
3. cloning of the gene neuron navigator-1 (NAV1), a human homolog of unc-53, a gene involved in axon guidance in Caenorhabditis elegans PMID: 12079279
亞細(xì)胞定位：

Cytoplasm, cytoskeleton.
蛋白家族：

Nav/unc-53 family
組織特異性：

Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.
數(shù)據(jù)庫鏈接：

HGNC: 15989

OMIM: 611628

KEGG: hsa:89796

STRING: 9606.ENSP00000356265

UniGene: Hs.585374