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NFATC2IP Antibody

  • 中文名稱：
    NFATC2IP兔多克隆抗體
  • 貨號：
    CSB-PA070052
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    NFATC2IP
  • 別名：
    45 kDa NF-AT-interacting protein antibody; 45 kDa NFAT-interacting protein antibody; cytoplasmic 2-interacting protein antibody; ESC2 antibody; NF2IP_HUMAN antibody; NFAT-interacting protein, 45-KD antibody; NFATC2-interacting protein antibody; Nfatc2ip antibody; NIP45 antibody; Nuclear factor of activated T-cells antibody; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein antibody; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein antibody; RAD60 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human NFATc2IP.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
  • 基因功能參考文獻(xiàn)：
    1. ZBTB25 functions as a negative regulator of nuclear factor of activated T cells (NF-AT) activation, such that RNA interference mediated knockdown resulted in enhanced activation of target genes. PMID: 20410506
  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25906

    OMIM: 614525

    KEGG: hsa:84901

    STRING: 9606.ENSP00000324792

    UniGene: Hs.513470