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NR2C2AP Antibody, HRP conjugated

  • 中文名稱：
    NR2C2AP兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA016053LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) NR2C2AP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NR2C2AP
  • 別名：
    nr2c2ap antibody; NR2CA_HUMAN antibody; Nuclear receptor 2C2 associated protein antibody; Nuclear receptor 2C2-associated protein antibody; Repressor for TR4 transactivation antibody; TR4 orphan receptor associated 16 kDa protein antibody; TR4 orphan receptor associated protein TRA16 antibody; TR4 orphan receptor-associated 16 kDa protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Nuclear receptor 2C2-associated protein (7-139AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
  • 基因功能參考文獻(xiàn)：
    1. High TRA16 expression promotes small cell lung carcinoma by activating estrogen receptor beta and blocking testicular orphan nuclear receptor 2 PMID: 23129017
    2. TRA16 may function as a novel repressor to selectively suppress the TR4-mediated transactivation PMID: 12486131
    3. Together, these findings provide the first in vivo evidence that an orphan nuclear receptor, such as TR4, may play major roles in the RA-mediated apoptosis or differentiation in P19 cells. PMID: 15381082
    4. Taken together, these results suggested that TR4 should be one of important regulators of OXT gene expression. PMID: 17054912
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    NR2C2AP family
  • 組織特異性：
    Expressed in all tissues examined, with highest expression in heart, skeletal muscle and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30763

    OMIM: 608719

    KEGG: hsa:126382

    STRING: 9606.ENSP00000332823

    UniGene: Hs.708153