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  4. NTAN1 Antibody, Biotin conjugated

NTAN1 Antibody, Biotin conjugated

  • 中文名稱：
    NTAN1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA822176LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) NTAN1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NTAN1
  • 別名：
    NTAN1 antibody; Protein N-terminal asparagine amidohydrolase antibody; EC 3.5.1.121 antibody; Protein NH2-terminal asparagine amidohydrolase antibody; PNAA antibody; Protein NH2-terminal asparagine deamidase antibody; PNAD antibody; Protein N-terminal Asn amidase antibody; Protein N-terminal asparagine amidase antibody; Protein NTN-amidase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein N-terminal asparagine amidohydrolase protein (219-310AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by NTAN1/PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position, nor on acetylated N-terminal peptidyl Asn.
  • 基因功能參考文獻：
    1. Results indicate that hNTAN1 is highly selective for the hydrolysis of N-terminal peptidyl L-Asn. PMID: 21375249
  • 亞細胞定位：
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29909

    OMIM: 615367

    KEGG: hsa:123803

    STRING: 9606.ENSP00000287706

    UniGene: Hs.592045