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NUDT6 Antibody

  • 中文名稱(chēng)：
    NUDT6兔多克隆抗體
  • 貨號(hào)：
    CSB-PA016176GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    NUDT6
  • 別名：
    NUDT6 antibody; FGF2AS antibody; Nucleoside diphosphate-linked moiety X motif 6 antibody; Nudix motif 6 antibody; EC 3.6.1.- antibody; Antisense basic fibroblast growth factor antibody; Protein GFG antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human NUDT6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May contribute to the regulation of cell proliferation.
  • 基因功能參考文獻(xiàn)：
    1. FGF-2 exhibits antitumor activity in vitro and correlates with expression of FGF receptors expression in medulloblastoma cells PMID: 11801566
    2. 18-kDa FGF-2 harbors a C-terminal nonclassical bipartite nuclear localization signal, a portion of which also regulates its nucleolar localization. PMID: 15247275
    3. The aim of this study was to characterize the expression of alternatively spliced FGF-AS transcripts and encoded nudix-motif proteins in normal human tissues and in esophageal adenocarcinoma. PMID: 17569023
    4. hydroxyapatite nanocrystals exposure up-regulated FGF-2 mRNA by 6 fold and increased 18 kDa protein isoform by 40% PMID: 17681892
    5. Thus, survivin, Smac, and PKC alpha might play important roles in the inhibition of apoptosis by FGF-2 in human small cell lung cancer cells. PMID: 18401527

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  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Mitochondrion. Note=Subcellular location may vary between isoforms.
  • 蛋白家族：
    Nudix hydrolase family
  • 組織特異性：
    Detected in liver, kidney and esophagus (at protein level). Ubiquitous.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 8053

    OMIM: 606261

    KEGG: hsa:11162

    STRING: 9606.ENSP00000306070

    UniGene: Hs.558459