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  4. OVOL1 Antibody

OVOL1 Antibody

  • 中文名稱：
    OVOL1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA017303LA01HU
  • 規(guī)格：
    ￥3,900
  • 圖片：
    • Western Blot
      Positive WB detected in: U251 whole cell lysate(20μg), MCF7 whole cell lysate(20μg), PC-3 whole cell lysate(20μg), 293T whole cell lysate(20μg), A549 whole cell lysate(20μg),Mouse Brain tissue lysate(20μg)
      All lanes: OVOL1 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31 kDa
      Observed band size: 31 kDa
      Exposure time: 30s
    • IHC image of CSB-PA017303LA01HU diluted at 1:50 and staining in paraffin-embedded human stomach tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
    • IHC image of CSB-PA017303LA01HU diluted at 1:50 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) OVOL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    OVOL1
  • 別名：
    hOvo1 antibody; Ovo homolog like 1 antibody; Ovo like 1(Drosophila) antibody; Ovo, Drosophila, homolog-like, 1 antibody; Ovol1 antibody; OVOL1_HUMAN antibody; Putative transcription factor Ovo like 1 antibody; Putative transcription factor Ovo-like 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Putative transcription factor Ovo-like 1 protein (9-267AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen?affinity?purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.02% sodium azide
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:3000
    IHC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system.
  • 基因功能參考文獻(xiàn)：
    1. OVOL1 is an integral part of the aryl hydrocarbon receptor-mediated mechanism of Filaggrin expression in human keratinocytes. PMID: 28703805
    2. that the OVOL1-OVOL2 axis may actively contribute to cell differentiation and proliferation in the hair bulb PMID: 26873447
    3. OVOL1 is a regulator of trophoblast progenitor cell fate during human trophoblast development. PMID: 26504231
    4. KIF3A and OVOL1 are involved in the development of Atopic dermatitis in the Chinese pediatric population. PMID: 26127003
    5. OVOL1 may play an important role in human skin morphogenesis and tumorigenesis. PMID: 25509883
    6. Association of KIF3A, but not OVOL1 and ACTL9, with atopic eczema in Italian patients PMID: 23278845
    7. Molecular phylogeny of OVOL1, OVOL2 and OVOL3 genes illustrates a conserved C2H2 zinc finger domain coupled by hypervariable unstructured regions in humans and other species PMID: 22737237

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  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in fetal kidney, and also in adult pancreas and placenta. Not expressed in intestine, peripheral blood lymphocytes and ovary.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 8525

    OMIM: 602313

    KEGG: hsa:5017

    STRING: 9606.ENSP00000337862

    UniGene: Hs.134434