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PCDH20 Antibody, HRP conjugated

  • 中文名稱：
    PCDH20兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA822719LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PCDH20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PCDH20
  • 別名：
    FLJ22218 antibody; PCD20_HUMAN antibody; PCDH 13 antibody; PCDH 20 antibody; PCDH13 antibody; PCDH20 antibody; Protocadherin 13 antibody; Protocadherin 20 antibody; Protocadherin-13 antibody; Protocadherin-20 antibody; Protocadherin13 antibody; Protocadherin20 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protocadherin-20 protein (61-360AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Potential calcium-dependent cell-adhesion protein.
  • 基因功能參考文獻：
    1. low expression of PCDH20 was found to be associated with poor OS in HCC patients; hence, this protein represents a promising potential prognostic biomarker PMID: 27935871
    2. Study shows that PCDH20 expression is downregulated in nasopharyngeal carcinoma cells (NPC) and identified it as a functional tumor suppressor and an important antagonist of Wnt/beta-catenin signaling and EMT, with frequent epigenetic inactivation in NPC. PMID: 25736877
    3. In conclusion, these data here strongly suggested that PCDH20 may act as a candidate tumour suppressor in hepatocellular carcinoma. PMID: 24910204
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14257

    OMIM: 614449

    KEGG: hsa:64881

    STRING: 9606.ENSP00000386653

    UniGene: Hs.391781