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PGLYRP2 Antibody, Biotin conjugated

  • 中文名稱：
    PGLYRP2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA846684LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PGLYRP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PGLYRP2
  • 別名：
    PGLYRP2 antibody; PGLYRPL antibody; PGRPL antibody; UNQ3103/PRO10102 antibody; N-acetylmuramoyl-L-alanine amidase antibody; EC 3.5.1.28 antibody; Peptidoglycan recognition protein 2 antibody; Peptidoglycan recognition protein long antibody; PGRP-L antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human N-acetylmuramoyl-L-alanine amidase protein (22-576AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
  • 基因功能參考文獻(xiàn)：
    1. This study demonistrated that PGLYRP2 single-nucleotide polymorphisms is risk of Parkinson's disease. PMID: 24838182
    2. Various types of human blood cells were tested for expression of the Tag7/PGRP-SA and TagL/PGRP-L proteins, which belong to the family of proteins possessing the lysozyme-like peptidoglycan recognition protein (PGRP) domain PMID: 12669421
    3. Serum N-acetylmuramoyl-l-alanine amidaseand liver PGLYRP2 are the same protein encoded by the pglyrp2 gene. PMID: 16054449
    4. PGLYRP2 may function in the skin and the eyes as an inducible scavenger of proinflammatory peptidoglycan. PMID: 16239516
    5. pglyrp2 expression in skin and liver is important for systemic and local innate immune responses to bacterial infections PMID: 16714290

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  • 亞細(xì)胞定位：
    Secreted. Membrane.
  • 蛋白家族：
    N-acetylmuramoyl-L-alanine amidase 2 family
  • 組織特異性：
    Strongly expressed in liver and fetal liver, and secreted into serum. Expressed to a much lesser extent in transverse colon, lymph nodes, heart, thymus, pancreas, descending colon, stomach and testis. Isoform 2 is not detected in the liver or serum.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30013

    OMIM: 608199

    KEGG: hsa:114770

    STRING: 9606.ENSP00000345968

    UniGene: Hs.282244